X-Chem, Inc.
Biotechnology ResearchMassachusetts, United States51-200 Employees
X-Chem, Inc. is a biotechnology research company focused on small-molecule discovery for pharmaceutical and biotech partners. It blends encoded-libraries approaches with discovery chemistry and AI to tackle difficult, high-value targets. The company reports an 80% rate of identifying functional hits, has licensed around 100 programs, and has produced four clinical candidates since 2021, with its methods validated across roughly 30 target classes. Based in Waltham, Massachusetts, the organization employs a mid-sized team and collaborates with clients across early-drug-discovery stages, offering integrated project support, screening follow-up, and access to its ArtemisAI platform. In May 2025, it expanded its collaboration with Orion Pharma to encompass the full early-stage discovery process from hit identification through candidate selection.