Insights

Innovative Biotech Focus Upstream Bio specializes in developing monoclonal antibodies targeting upstream drivers of inflammatory responses, indicating strong opportunities for partnerships with pharmaceutical companies seeking novel immunomodulatory therapies.

Recent Public Funding Having successfully raised $255 million through an IPO and an additional $200 million in Series B funding, Upstream Bio demonstrates robust market confidence and readiness for scaled collaboration, licensing, or co-development opportunities.

Clinical Data Transparency The company's active engagement in presenting structural and mechanistic data at major respiratory congresses suggests openness to research collaborations and potential needs for laboratory, data management, or assay technology providers.

Leadership Growth Strategic hires of experienced executives, including a veteran general counsel and a new CEO, indicate a focus on organizational expansion and operational scaling, creating opportunities for professional services and management consulting partners.

Market Positioning With a focus on inflammatory disease and mid-stage clinical trials in asthma and sinusitis, Upstream Bio presents potential sales avenues in clinical trial support, specialized biotech reagents, and patient recruitment services aligned with its development pipeline.

Upstream Bio Tech Stack

Upstream Bio uses 8 technology products and services including MySQL, Squarespace Commerce, Google Fonts API, and more. Explore Upstream Bio's tech stack below.

  • MySQL
    Database
  • Squarespace Commerce
    E-commerce
  • Google Fonts API
    Font Scripts
  • Lightbox
    Javascript Libraries
  • PHP
    Programming Languages
  • Yoast SEO
    Search Engines
  • Cloudflare Bot Management
    Security
  • HTTP/3
    Web & Portal Technology

Media & News

Upstream Bio's Email Address Formats

Upstream Bio uses at least 1 format(s):
Upstream Bio Email FormatsExamplePercentage
First.Last@upstreambio.comJohn.Doe@upstreambio.com
50%
First.Last@upstreambio.comJohn.Doe@upstreambio.com
50%

Frequently Asked Questions

Where is Upstream Bio's headquarters located?

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Upstream Bio's main headquarters is located at 890 Winter Street Suite 200 Waltham, Massachusetts 02451 United States. The company has employees across 3 continents, including North AmericaEuropeSouth America.

What is Upstream Bio's stock symbol?

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Upstream Bio is a publicly traded company; the company's stock symbol is UPB.

What is Upstream Bio's official website and social media links?

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Upstream Bio's official website is upstreambio.com and has social profiles on LinkedInCrunchbase.

What is Upstream Bio's SIC code NAICS code?

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Upstream Bio's SIC code is 8733 - Noncommercial Research Organizations NAICS code is 541714 - Research and Development in Biotechnology (except Nanobiotechnology).

How many employees does Upstream Bio have currently?

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As of March 2026, Upstream Bio has approximately 74 employees across 3 continents, including North AmericaEuropeSouth America. Key team members include Chief Business Officer: A. H.Chief Financial And Chief Operating Officer: M. G.Chief Technology Officer: S. P. P.. Explore Upstream Bio's employee directory with LeadIQ.

What industry does Upstream Bio belong to?

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Upstream Bio operates in the Biotechnology Research industry.

What technology does Upstream Bio use?

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Upstream Bio's tech stack includes MySQLSquarespace CommerceGoogle Fonts APILightboxPHPYoast SEOCloudflare Bot ManagementHTTP/3.

What is Upstream Bio's email format?

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Upstream Bio's email format typically follows the pattern of First.Last@upstreambio.com. Find more Upstream Bio email formats with LeadIQ.

How much funding has Upstream Bio raised to date?

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As of March 2026, Upstream Bio has raised $200M in funding. The last funding round occurred on Jun 08, 2023 for $200M.

When was Upstream Bio founded?

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Upstream Bio was founded in 2021.

Upstream Bio

Biotechnology ResearchMassachusetts, United States51-200 Employees

We are advancing verekitug, a clinical-stage monoclonal antibody targeting an upstream driver of inflammatory response. Our experienced team is committed to leveraging verekitug’s unique mechanism of action to improve the treatment options for millions of patients living with severe inflammatory diseases.

Section iconCompany Overview

Headquarters
890 Winter Street Suite 200 Waltham, Massachusetts 02451 United States
SIC Code
8733 - Noncommercial Research Organizations
Stock Symbol
UPB
NAICS Code
541714 - Research and Development in Biotechnology (except Nanobiotechnology)
Founded
2021
Employees
51-200

Section iconFunding & Financials

  • $200M

    Upstream Bio has raised a total of $200M of funding over 4 rounds. Their latest funding round was raised on Jun 08, 2023 in the amount of $200M.

  • $25M$50M

    Upstream Bio's revenue is estimated to be in the range of $25M$50M

Section iconFunding & Financials

  • $200M

    Upstream Bio has raised a total of $200M of funding over 4 rounds. Their latest funding round was raised on Jun 08, 2023 in the amount of $200M.

  • $25M$50M

    Upstream Bio's revenue is estimated to be in the range of $25M$50M

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