Sermonix Pharmaceuticals
Pharmaceutical ManufacturingOhio, United States2-10 Employees
Sermonix Pharmaceuticals is a small biopharmaceutical company based in Columbus, Ohio, focused on developing targeted therapeutics for ESR1-mutated metastatic breast and gynecological cancers. Its clinical program centers on lasofoxifene, an oral endocrine agent evaluated in the ELAINE studies for patients with locally advanced or metastatic ER+/HER2- breast cancer carrying ESR1 mutations, including both women and men. The company was founded by David Portman, MD, a clinician known for women's health research. Operating within the pharmaceutical manufacturing sector, Sermonix aims to advance treatments for a specific cancer subset through targeted therapies. In 2025, it announced a collaboration with Regor Pharmaceuticals to blend Sermonix's clinical drug development experience with Regor's computational discovery technology to advance metastatic breast cancer treatment.