Septerna
Biotechnology ResearchCalifornia, United States51-200 Employees
Septerna is a biotechnology research company based in South San Francisco, California, focused on discovering and developing medicines that target G protein-couped receptors (GPCRs). The company combines biochemical, structural, and computational drug discovery approaches and operates an industrialized platform to modulate GPCR biology, including its Native Complex Platform to expand the druggable GPCR landscape. Septerna has a workforce of 51-200 employees and is headquartered in the California location. Public disclosures indicate revenue in the range of $50 million to $100 million and total funding of about $150 million. In April 2026, Septerna announced initiation of a Phase 1 trial for SEP-479, an oral PTH1R agonist for hypoparathyroidism, and the company continues to report progress in its clinical programs. The company trades on Nasdaq under the ticker SEPN.