Puracyp, Inc.
Biotechnology ResearchCalifornia, United States2-10 Employees
Puracyp, Inc. is a small biotechnology firm based in Carlsbad, California, focused on developing methods for rapid and reliable safety assessment of new drugs before they enter clinical testing. It provides cell-based systems to evaluate activation of nuclear receptors, an initial step in inducing drug-metabolizing enzymes, with primary assays targeting human and rat PXR (SXR) and AhR. The company also conducts studies to determine metabolic stability and kinetics of metabolism, along with P450 reaction phenotyping and assessment of inhibition of P450 oxidation by new chemical entities. Additionally, Puracyp supplies tools to study oxidative drug metabolism in vitro, including well-characterized human liver microsomes and antibodies specific to individual P450 enzymes, designed for high-throughput work without compromising quality. Within the biotechnology research industry, Puracyp provides services to drug discovery programs, helping clients understand nuclear receptor activity and metabolic pathways that influence drug safety. With a focus on high-throughput workflows that do not compromise quality, the company performs its work from its Carlsbad location in California.