Pretzel Therapeutics Email Format
Biotechnology ResearchMassachusetts, United States11-50 Employees
Pretzel Therapeutics is a biotechnology company focused on developing therapies aimed at reversing mitochondrial dysfunction by leveraging a deep mechanistic understanding of mitochondrial biology. Its work targets a broad range of conditions linked to mitochondrial decline, including mitochondrial diseases and aging-related disorders, with an emphasis on addressing the genetic drivers of dysfunction to potentially benefit multiple disease areas. Based in Boston, Massachusetts, the company operates within the biotechnology research sector and pursues first-in-class therapeutics that seek to restore cellular energy production at its source. The organization describes a research emphasis on cellular energetics and has engaged in notable collaborations and presentations to share preclinical findings, including work on its lead program PX578 and other targets related to mitochondrial function. Recent activities include participation in scientific conferences to communicate preclinical data and partnerships that support its mission in pursuing treatments for neurological, muscle, metabolic, and rare diseases.