Oncotelic
Biotechnology ResearchCalifornia, United States11-50 Employees
Oncotelic is a clinical-stage biotechnology company based in Calabasas, California, focused on cancer and other serious diseases. By addressing key reasons drugs fail in the clinic—immune suppression, fibrosis, limited tissue penetration, resistance, and delivery limitations—it advances TGFB2-targeted therapeutics and pushes programs into late-stage development through strategic joint ventures. A major component of its strategy is Sapu Therapeutics, its majority-owned joint venture that pairs TGFB2 programs with nanomedicine and outlines a path to a Hong Kong IPO. The company also develops ultra-small molecular nanomedicine to improve tissue penetration and pharmacology, and it operates PDAOAI, an AI-driven platform for evidence interrogation that supports hypothesis generation, biomarker discovery, and translational insight. In June 2026, Oncotelic announced the launch of an AI-powered GMP manufacturing services platform, reflecting its emphasis on partnerships, efficient development, and scalable manufacturing capabilities.