Nuvalent, Inc.
Biotechnology ResearchMassachusetts, United States201-500 Employees
Nuvalent, Inc. is a clinical-stage biotechnology company focused on developing precisely targeted cancer therapies that address clinically validated kinase targets. Using structure-based design, it aims to produce small molecules with strong target selectivity to overcome resistance and reduce adverse events, with the goal of more durable responses. Its lead programs focus on ROS1-positive and ALK-positive non-small cell lung cancer, complemented by multiple discovery-stage research efforts. Based in Cambridge, Massachusetts, Nuvalent operates within the biotechnology research industry. Nuvalent serves the oncology research and clinical community seeking targeted kinase inhibitors and, through collaborations, works with diagnostic partners to support cancer care. In 2026, the company announced a multi-year collaboration with Guardant Health to develop companion diagnostics for its oncology programs, aligning diagnostic capabilities with its targeted therapies.