Gelesis Email Format

Biotechnology ResearchApulia, Italy51-200 Employees

Gelesis is a mid-sized biotechnology company based in Calimera, in the Apulia region of Italy, focused on metabolic disease research. Its lead product, Plenity, is an orally administered, non-systemic hydrogel that has FDA clearance for weight management in adults with a BMI of 25 to 40 when used with diet and exercise. The company describes its portfolio as consumer-centered biotherapeutics, with additional therapies under development for Type 2 Diabetes, NAFLD/NASH, and Functional Constipation. By working at the intersection of weight management and gut health, Gelesis seeks to influence metabolic outcomes through a digestive-system local mechanism. 
Gelesis operates in the biotechnology research sector with a mission to support patients, healthcare professionals, and society in addressing metabolic disease. A notable development in its scientific program occurred in 2023, when Cell Reports Medicine published preclinical findings suggesting that its oral hydrogel may promote weight loss and improve metabolic health by influencing the gut-liver axis.

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