Esse Health
Medical PracticesMissouri, United States501-1000 Employees
Esse Health is a physician-led medical practice group serving the St. Louis area, emphasizing joint decision-making between patients and their clinicians. The organization focuses on prevention and coordinated care to help people stay healthy and access care when needed. It comprises more than 100 independent physicians operating across 45 offices, making it the region’s largest doctor-owned group. The group is based in the St. Louis region, with a street address at 12655 Olive Boulevard, Missouri 63141. In 2025 it experienced a data breach affecting more than 263,000 patients, with a $2.53 million settlement reached in 2026.