Insights

Acquisition target Cullgen is in the process of a potential acquisition by Gyre Therapeutics in a substantial all-stock deal valued around $300M, indicating a high likelihood of strategic continuity or partnership considerations for buyers or collaborators in targeted protein degradation.

Pipeline acceleration With uSMITE technology enabling degradation of undruggable intracellular targets and a strategy to build both internal candidates and E3 ligand portfolios, there is a strong opportunity to position other biotech and pharma partners as co-developers or licensees for expanded target spaces.

Clinical development depth Past leadership in clinical development and key executives, along with a Series C funding history, signals readiness for late-stage collaborations, co-development deals, or access to translational biomarkers that could be valuable to larger partners seeking early- to mid-phase assets.

Strategic partnerships Existing collaborations, notably with Astellas Pharma and AstraZeneca-CICC Venture partners, suggest a favorable track record and appetite from major players for future alliance structures such as licensing, joint development, or strategic investments.

Financial foothold Current funding of over one hundred million and reported revenue in the tens of millions imply a solid financial runway for offtake discussions, milestone-driven partnerships, and co-funded trials with potential acquirers or licensees seeking near-term commercialization potential.

Similar companies to Cullgen Inc.

Cullgen Inc. Tech Stack

Cullgen Inc. uses 8 technology products and services including Squarespace, WordPress, NetSuite, and more. Explore Cullgen Inc.'s tech stack below.

Media & News

Cullgen Inc.'s Email Address Formats

Cullgen Inc. uses at least 2 email formats:
Cullgen Inc. Email FormatsExamplePercentage
First.Last@cullgen.comJohn.Doe@cullgen.com
94%
FLast@cullgen.comJDoe@cullgen.com
6%

Frequently Asked Questions

What is Cullgen Inc.'s official website and social media links?

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Cullgen Inc.'s official website is cullgen.com and has social profiles on LinkedIn and Crunchbase.

How much revenue does Cullgen Inc. generate?

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As of October 2026, Cullgen Inc.'s annual revenue is estimated to be $10M - $25M.

What is Cullgen Inc.'s SIC code and NAICS code?

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Cullgen Inc.'s SIC code is 8731 - Commercial Physical and Biological Research and NAICS code is 541714 - Research and Development in Biotechnology (except Nanobiotechnology).

How many employees does Cullgen Inc. have currently?

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As of October 2026, Cullgen Inc. has approximately 25 employees across 3 continents, including North America, Asia and Europe. Key team members include Vice President Of Discovery Medicine: X. H., Chairman And Chief Executive Officer: Y. L. and Senior Director Of Medicinal Chemistry: C. Z. Explore Cullgen Inc.'s employee directory with LeadIQ.

What industry does Cullgen Inc. belong to?

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Cullgen Inc. operates in the Biotechnology Research industry.

What technology does Cullgen Inc. use?

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Cullgen Inc.'s tech stack includes Squarespace, WordPress, NetSuite, Squarespace Commerce, parallax.js, AfterPay, Box and Adobe Creative Suite.

What is Cullgen Inc.'s email format?

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Cullgen Inc.'s email format typically follows the pattern of First.Last@cullgen.com. Find more Cullgen Inc. email formats with LeadIQ.

How much funding has Cullgen Inc. raised to date?

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As of October 2026, Cullgen Inc. has raised $106M in funding. The last funding round occurred on May 08, 2023 for $35M.

When was Cullgen Inc. founded?

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Cullgen Inc. was founded in 2018.
Cullgen Inc. logo

Cullgen Inc.

Biotechnology ResearchCalifornia, United States11-50 Employees

Cullgen Inc. is a San Diego, California-based biotechnology company pursuing targeted protein degradation. Its uSMITE platform harnesses the cell's ubiquitin-proteasome system to selectively eliminate disease-causing intracellular proteins, including a large portion often deemed undruggable by conventional small molecules. The company is advancing its own pipeline while also developing a portfolio of novel E3 ligands to expand its therapeutic modalities.

Operating in the biotechnology research industry, Cullgen positions itself as a developer of protein degraders intended to broaden the range of addressable disease targets. Its customers are researchers and biopharmaceutical developers seeking new approaches to intracellular proteins that lack effective therapeutic options. In March 2026, Gyre Therapeutics announced an agreement to acquire Cullgen in an all-stock transaction.

Section iconCompany Overview

SIC Code
8731 - Commercial Physical and Biological Research
NAICS Code
541714 - Research and Development in Biotechnology (except Nanobiotechnology)
Founded
2018
Employees
11-50

Section iconFunding & Financials

  • $106M

    Cullgen Inc. has raised a total of $106M of funding over 5 rounds. Their latest funding round was raised on May 08, 2023 in the amount of $35M as a Corporate Round.

  • $10M - $25M

    Cullgen Inc.'s revenue is estimated to be in the range of $10M - $25M

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